{"id":8831,"date":"2017-12-05T08:28:10","date_gmt":"2017-12-05T08:28:10","guid":{"rendered":"http:\/\/old.institutcataladelpeu.com\/?p=8831"},"modified":"2018-07-20T08:39:28","modified_gmt":"2018-07-20T08:39:28","slug":"the-klippel-trenaunay-weber-syndrome-definition-and-fetaures","status":"publish","type":"post","link":"https:\/\/old.institutcataladelpeu.com\/en\/the-klippel-trenaunay-weber-syndrome-definition-and-fetaures\/","title":{"rendered":"THE KLIPPEL-TRENAUNAY-WEBER SYNDROME. DEFINITION AND FEATURES."},"content":{"rendered":"<p>Klippel-Trenaunay-Weber syndrome is a congenital affectation of osseous development, blood vessels and soft tissues.<\/p>\n<p>The main features of this syndrome are:<\/p>\n<ul>\n<li>The appearance of a red birthmark called a port-wine stains or hemangioma planum in birth. It appears approximately in 90% of cases and it is located in legs, buttocks and abdomen. These stains may affect the subcutaneous tissue, bones, muscles or organs like the spleen, the liver or the colon.<\/li>\n<li>Increase in osseous growth and soft tissues. It may appear at birth and it develops throughout infancy. It grows both in osseous length and thickness, mostly as result of\u00a0 to the growth of soft tissues.<\/li>\n<li>The appearance of varicose veins. They are congenital and they are not detected until the child starts walk. They are located under the knee or laterally. When it is located above the knee, it affects to superficial and deep venous systemsand even certain organs.<\/li>\n<\/ul>\n<p>Other complications of the Klippel-Trenaunay-Weber syndrome are lymphatic malformations at an obstructive or lymphedema level, as well as facial asymmetry, changes in the size of the head, syndactyly, paresthesia, decalcification, thrombosis, ulcers, etc.<\/p>\n<p>The excessive growth of bones and soft tissues appear\u00a0 in infancy and\u00a0 usually affects only one leg (although it can also affect the torso and the arms). The affected leg by this excessive growth may experience pain, problems with walking or a feeling of heaviness.<\/p>\n<p>The Klippel-Trenaunay-Weber syndrome has an unknown cause although it has a relation with the mutation of the <strong><em>PIK3CA<\/em><\/strong> gene associated with excessive growth.<\/p>\n<p>The diagnosis must be done through a computerized tomography, magnetic resonance imaging, echography and lymphoscintiegraphy. The differential diagnosis must include venous dysplasia, lymphedema and osseous tumours.<\/p>\n<p>Klippel-Trenaunay-Weber syndrome is a progressive benign process whose treatment is symptomatic and conservative in 60% of the cases.<\/p>\n<p>Surgery is usually recommended when there is a lymphedema, cellulitis and a chronic venous insufficiency. The epiphysiodesis is also a technique that decreases excessive bone growths.<\/p>\n<p>Sclerotherapy is non-surgical treatments used to normalise the flow of blood in the affected veins.<\/p>\n<p>Compression clothing is also used to complement\u00a0 other procedures to reduce the volume through the use of intermittent pneumatic devices (they inflate and deflate at fixed intervals).<\/p>\n<div id=\"attachment_8811\" style=\"width: 455px\" class=\"wp-caption alignnone\"><img  title=\"THE KLIPPEL-TRENAUNAY-WEBER SYNDROME. DEFINITION AND FEATURES.\" loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-8811\" class=\"wp-image-8811\" src=\"http:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-1-1.jpg\"  alt=\"THE KLIPPEL-TRENAUNAY-WEBER SYNDROME. DEFINITION AND FEATURES.\"  width=\"445\" height=\"334\" srcset=\"https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-1-1.jpg 489w, https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-1-1-312x234.jpg 312w, https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-1-1-450x338.jpg 450w\" sizes=\"auto, (max-width: 445px) 100vw, 445px\" \/><p id=\"caption-attachment-8811\" class=\"wp-caption-text\">Klippel-Trenaunay-Weber syndrome.<\/p><\/div>\n<p>&nbsp;<\/p>\n<div id=\"attachment_8812\" style=\"width: 375px\" class=\"wp-caption alignnone\"><img  title=\"THE KLIPPEL-TRENAUNAY-WEBER SYNDROME. DEFINITION AND FEATURES.\" loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-8812\" class=\"wp-image-8812\" src=\"http:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-2-1.jpg\"  alt=\"THE KLIPPEL-TRENAUNAY-WEBER SYNDROME. DEFINITION AND FEATURES.\"  width=\"365\" height=\"487\" srcset=\"https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-2-1.jpg 594w, https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-2-1-176x234.jpg 176w, https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-2-1-529x705.jpg 529w, https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-2-1-450x600.jpg 450w\" sizes=\"auto, (max-width: 365px) 100vw, 365px\" \/><p id=\"caption-attachment-8812\" class=\"wp-caption-text\">Klippel-Trenaunay-Weber syndrome. You can see the bigger size of the left foot.<\/p><\/div>\n<p>&nbsp;<\/p>\n<div id=\"attachment_8813\" style=\"width: 375px\" class=\"wp-caption alignnone\"><img  title=\"THE KLIPPEL-TRENAUNAY-WEBER SYNDROME. DEFINITION AND FEATURES.\" loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-8813\" class=\"wp-image-8813\" src=\"http:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-3-1.jpg\"  alt=\"THE KLIPPEL-TRENAUNAY-WEBER SYNDROME. DEFINITION AND FEATURES.\"  width=\"365\" height=\"487\" srcset=\"https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-3-1.jpg 490w, https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-3-1-176x234.jpg 176w, https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-3-1-450x600.jpg 450w\" sizes=\"auto, (max-width: 365px) 100vw, 365px\" \/><p id=\"caption-attachment-8813\" class=\"wp-caption-text\">Klippel-Trenaunay-Weber syndrome. You can see the appearance of Port-wine stains.<\/p><\/div>\n<p>&nbsp;<\/p>\n<div id=\"attachment_8814\" style=\"width: 477px\" class=\"wp-caption alignnone\"><img  title=\"THE KLIPPEL-TRENAUNAY-WEBER SYNDROME. DEFINITION AND FEATURES.\" loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-8814\" class=\"wp-image-8814\" src=\"http:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-4-1.jpg\"  alt=\"THE KLIPPEL-TRENAUNAY-WEBER SYNDROME. DEFINITION AND FEATURES.\"  width=\"467\" height=\"350\" srcset=\"https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-4-1.jpg 588w, https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-4-1-312x234.jpg 312w, https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-4-1-450x338.jpg 450w\" sizes=\"auto, (max-width: 467px) 100vw, 467px\" \/><p id=\"caption-attachment-8814\" class=\"wp-caption-text\">Klippel-Trenaunay-Weber syndrome. You can see the appearance of varicose veins.<\/p><\/div>\n<p>&nbsp;<\/p>\n<div id=\"attachment_8815\" style=\"width: 353px\" class=\"wp-caption alignnone\"><img  title=\"THE KLIPPEL-TRENAUNAY-WEBER SYNDROME. DEFINITION AND FEATURES.\" loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-8815\" class=\"wp-image-8815 size-full\" src=\"http:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-5-1.jpg\"  alt=\"THE KLIPPEL-TRENAUNAY-WEBER SYNDROME. DEFINITION AND FEATURES.\"  width=\"343\" height=\"457\" srcset=\"https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-5-1.jpg 343w, https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-5-1-176x234.jpg 176w\" sizes=\"auto, (max-width: 343px) 100vw, 343px\" \/><p id=\"caption-attachment-8815\" class=\"wp-caption-text\">Klippel-Trenaunay-Weber syndrome. You can see the thickness difference between both extremities.<\/p><\/div>\n<p>&nbsp;<\/p>\n<div id=\"attachment_8816\" style=\"width: 467px\" class=\"wp-caption alignnone\"><img  title=\"THE KLIPPEL-TRENAUNAY-WEBER SYNDROME. DEFINITION AND FEATURES.\" loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-8816\" class=\"wp-image-8816 size-full\" src=\"http:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-6-1.jpg\"  alt=\"THE KLIPPEL-TRENAUNAY-WEBER SYNDROME. DEFINITION AND FEATURES.\"  width=\"457\" height=\"343\" srcset=\"https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-6-1.jpg 457w, https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-6-1-312x234.jpg 312w, https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-6-1-450x338.jpg 450w\" sizes=\"auto, (max-width: 457px) 100vw, 457px\" \/><p id=\"caption-attachment-8816\" class=\"wp-caption-text\">Klippel-Trenaunay-Weber syndrome. You can see the difference of both front parts of feet.<\/p><\/div>\n<p>&nbsp;<\/p>\n<div id=\"attachment_8817\" style=\"width: 467px\" class=\"wp-caption alignnone\"><img  title=\"THE KLIPPEL-TRENAUNAY-WEBER SYNDROME. DEFINITION AND FEATURES.\" loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-8817\" class=\"wp-image-8817 size-full\" src=\"http:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-7-1.jpg\"  alt=\"THE KLIPPEL-TRENAUNAY-WEBER SYNDROME. DEFINITION AND FEATURES.\"  width=\"457\" height=\"343\" srcset=\"https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-7-1.jpg 457w, https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-7-1-312x234.jpg 312w, https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-foto-7-1-450x338.jpg 450w\" sizes=\"auto, (max-width: 457px) 100vw, 457px\" \/><p id=\"caption-attachment-8817\" class=\"wp-caption-text\">Klippel-Trenaunay-Weber syndrome. You can see the asymmetry of the plantar footprint of the front part of the foot.<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Klippel-Trenaunay-Weber syndrome is a congenital affectation of osseous development, blood vessels and soft tissues. The main features of this syndrome are: The appearance of a red birthmark called a port-wine stains or hemangioma planum in birth. It appears approximately in 90% of cases and it is located in legs, buttocks and abdomen. These stains may [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":8818,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[283,277,344,280,304],"tags":[],"class_list":["post-8831","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-articles-2","category-dermatological-disorders","category-icp-en","category-others","category-pathology"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>THE KLIPPEL-TRENAUNAY-WEBER SYNDROME. DEFINITION AND FEATURES. - Institut Catal\u00e0 del Peu<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"THE KLIPPEL-TRENAUNAY-WEBER SYNDROME. DEFINITION AND FEATURES. - Institut Catal\u00e0 del Peu\" \/>\n<meta property=\"og:description\" content=\"Klippel-Trenaunay-Weber syndrome is a congenital affectation of osseous development, blood vessels and soft tissues. The main features of this syndrome are: The appearance of a red birthmark called a port-wine stains or hemangioma planum in birth. It appears approximately in 90% of cases and it is located in legs, buttocks and abdomen. These stains may [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/old.institutcataladelpeu.com\/en\/the-klippel-trenaunay-weber-syndrome-definition-and-fetaures\/\" \/>\n<meta property=\"og:site_name\" content=\"Institut Catal\u00e0 del Peu\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/institutcataladelpeu\/\" \/>\n<meta property=\"article:published_time\" content=\"2017-12-05T08:28:10+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2018-07-20T08:39:28+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/old.institutcataladelpeu.com\/wp-content\/uploads\/2017\/11\/sindrome-de-kipplel-Trenanay-portada-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"343\" \/>\n\t<meta property=\"og:image:height\" content=\"457\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Miguel \u00c1ngel Ba\u00f1os Bernad\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@ICPeu\" \/>\n<meta name=\"twitter:site\" content=\"@ICPeu\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Miguel \u00c1ngel Ba\u00f1os Bernad\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/old.institutcataladelpeu.com\\\/en\\\/the-klippel-trenaunay-weber-syndrome-definition-and-fetaures\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/old.institutcataladelpeu.com\\\/en\\\/the-klippel-trenaunay-weber-syndrome-definition-and-fetaures\\\/\"},\"author\":{\"name\":\"Miguel \u00c1ngel Ba\u00f1os Bernad\",\"@id\":\"https:\\\/\\\/old.institutcataladelpeu.com\\\/en\\\/#\\\/schema\\\/person\\\/d2ccc8088f9445f3e2758c2a60caf354\"},\"headline\":\"THE KLIPPEL-TRENAUNAY-WEBER SYNDROME. 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